Arrhythmias & electrophysiology

Echocardiography-Guided Radiofrequency Ablation for Cardiac Tumors

JACC CardioOncolPublished Case series

Authors' conclusion

TARFACT is a novel palliative treatment option for cardiac tumors, reducing accessible tumors and improving clinical symptoms in a preliminary group of patients.

Study context

Population
Patients with cardiac tumors (mucinous liposarcoma, myocardial hypertrophy with inflammatory cell infiltration mass, fibrous tissue tumor hyperplasia, myocardial clear cell sarcoma, cardiac rhabdomyoma)
Participants
5 patients
Exposure
Tumor size, symptoms and cardiac function before vs after transapical radiofrequency ablation for cardiac tumors (TARFACT)
  • TARFACTn = 5
Outcome
Safety and efficacy of TARFACT
Methodological detailsechocardiography-guided, transapical
  • Echocardiography-guided
  • Transapical

Main finding

As reported in the abstract

Tumor size · median follow-up 9 (range 4-12) months
GroupValueWidth (mean ± SD)
Before TARFACTmean 6.7 (SD 2.0) cm5.0 ± 2.1 cm
After TARFACTmean 4.7 (SD 1.8) cm2.5 ± 0.7 cm

Value

Before TARFACTmean 6.7 (SD 2.0) cm
After TARFACTmean 4.7 (SD 1.8) cm

Width (mean ± SD)

Before TARFACT5.0 ± 2.1 cm
After TARFACT2.5 ± 0.7 cm
  • After TARFACT vs Before TARFACT: P = 0.007 — length
  • After TARFACT vs Before TARFACT: P = 0.041 — width

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Echocardiography-Guided Radiofrequency Ablation for Cardiac Tumors. JACC CardioOncol. Published 30 April 2024. doi:10.1016/j.jaccao.2024.03.008

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