Angiographic characteristics of patients with STEMI and COVID-19: Insights from NACMI registry
Authors' conclusion
In patients with COVID-19 and STEMI, thrombus burden was pervasive with notable rates of multivessel thrombotic disease and stent thrombosis.
Study context
- Population
- Patients with COVID-19 and STEMI, NACMI Registry (North America)182 underwent percutaneous coronary intervention (PCI)
- Participants
- 234 patients
- Exposure
- Successful PCI vs Partially successful PCI vs Unsuccessful PCI
- Unsuccessful PCIn = 60
- Outcome
- Angiographic characteristics: culprit lesion(s), TIMI flow, thrombus grade burden, PCI outcome
Methodological detailscore laboratory angiographic analysis, independent core lab
- Core laboratory angiographic analysis
- Independent core lab
Main finding
As reported in the abstract
Angiographic characteristics
- One culprit lesion
- 74%
- Multiple culprits
- 14%
- No culprit identified
- 12%
- Multivessel thrombotic disease
- 27%
- Multivessel CAD
- 53%
- Stent thrombosis as presentation
- 12%
- Stent thrombosis in patients with previous coronary stents
- 55%
- Unsuccessful PCI (of 182 with PCI)
- 60 (33%)
- Unsuccessful PCI: post-PCI Thrombolysis In Myocardial Infarction (TIMI) flow <3
- 43/60
- Unsuccessful PCI: residual high thrombus burden
- 41/60
- Unsuccessful PCI: thrombus related complications
- 27/60
Observational data: associations, not effects.
Further findings
| Outcome | Successful PCI | Partially successful PCI | Unsuccessful PCI | RR (95% CI) | P value | |
|---|---|---|---|---|---|---|
| In-hospital mortality by PCI outcomeUnadjusted | 14% | 13% | 27% | 1.96 (1.05–3.66) | P = 0.03 | |
| In-hospital mortality by PCI outcomeAdjusted | 1.24 (0.65–2.34) | P = 0.51 | ||||
| 0.20.5125Relative risk (log scale) |
Original publication
Angiographic characteristics of patients with STEMI and COVID-19: Insights from NACMI registry. Am Heart J. Published 22 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →