Congenital heart diseaseSecondary analysis
Anxiety and Depression in Adults With Congenital Heart Disease
- Secondary analysis of the APPROACH-IS study
- multisite
- 15 countries
Authors' conclusion
In this global sample of adults with congenital heart disease, almost one-third reported elevated symptoms of depression and/or anxiety, which in turn were associated with lower QOL and HS.
Study context
- Population
- Adults with congenital heart disease
- Participants
- 3,815 adults · 15 countries
- Primary endpoint
- Prevalence of elevated depression and anxiety symptoms (HADS-A or HADS-D subscale ≥8)
Primary result
As reported in the abstract
Elevated symptoms (HADS ≥8)
Elevated symptoms in one or both subscales: 1,148
30.1%
Elevated HADS-A only
18.3%
Elevated HADS-D only
2.9%
Elevated on both subscales
8.9%
Further findings
Quality of life (QOL) and health status (HS) (0–100 analogue scales) by HADS-A and HADS-D symptom category
- QOL and HS decreased with increasing HADS-A and HADS-D symptom categories
- P < 0.001
Original publication
Anxiety and Depression in Adults With Congenital Heart Disease. J Am Coll Cardiol. Published 23 January 2024. doi:10.1016/j.jacc.2023.10.043
Summarised from the published abstract; every number is checked against it