Aortic & peripheral vascular disease
Aortic aneurysms in a general population cohort: prevalence and risk factors in men and women
Authors' conclusion
Subclinical AAs are four times more prevalent in men than in women. In both sexes, increasing age and BSA are risk factors for AAs of any anatomical location. Whereas arterial hypertension is a risk factor for TAAs, hypercholesterolaemia and smoking are risk factors for AAAs.
Study context
- Population
- General population (Copenhagen General Population Study), mean age 62 (range 40–95) years, CT angiography of the aorta56% women
- Participants
- 11,294 participants
- Exposure
- Men vs women
- Outcome
- Prevalence of TAA (ascending ≥45 mm, descending ≥35 mm) and AAA (abdominal ≥30 mm) and their risk factors
Methodological detailspopulation-based
- Population-based
Main finding
As reported in the abstract
Prevalence of aortic aneurysms
P < 0.001
- Prevalence in total population
- 2.1%
Observational data: associations, not effects.
Further findings
Risk factors for aortic aneurysms
- Thoracic aortic aneurysm (TAA): hypertension, OR
- 2.0 (1.5-2.8) (95% CI)
- Abdominal aortic aneurysm (AAA): hypercholesterolaemia, OR
- 2.4 (1.6-3.6) (95% CI)
- AAA: smoking, OR
- 3.2 (1.9-5.4) (95% CI)
- Aortic aneurysms (AAs) independently associated with male sex, increasing age and body surface area (BSA)
Original publication
Aortic aneurysms in a general population cohort: prevalence and risk factors in men and women. Eur Heart J Cardiovasc Imaging. Published 25 April 2024. doi:10.
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