Arrhythmias & electrophysiology
Are there pulmonary vein geometrical features associated with reconnection after pulsed field ablation of atrial fibrillation?
Authors' conclusion
The impact of the anatomical characteristics of PVs on PV reconnection was limited, confirming the ability of the PFA pentaspline catheter to adapt to various PV anatomies.
Study context
- Population
- Atrial fibrillation (AF) patients treated with pulsed field ablation (PFA) using the pentaspline catheter who experienced arrhythmia recurrence and underwent a second procedure with high-resolution mapping of the left atriumpatients (median age 65 years, 69% males), corresponding to 398 pulmonary vein (PVs)
- Participants
- 99 patients
- Comparison
- Anatomical and geometrical features of the PV ostia on pre-ablation computed tomography vs PV reconnection
- Outcome
- At least 1 reconnected PV
Main finding
As reported in the abstract
Patients with at least 1 reconnected PV
69%
Further findings
| Outcome | aOR (per 1 mm increase) (95% CI) | P value | |
|---|---|---|---|
| Association of long-axis diameter with PV reconnection | 1.06 (1.00–1.12) | P = 0.04 | |
| Association of difference in lateral angulation between ipsilateral PVs with PV reconnection | 1.02 (1.00–1.03) | P < 0.01 | |
| 0.512Adjusted odds ratio (log scale) |
PV reconnection rate
- PV reconnection rate ranged from
- 30% to 37%
- No significant difference between PVs
Discrimination of long-axis diameter and lateral angulation difference for PV reconnection
- Area under the receiver operator characteristic curve for both parameters
- <0.70
Original publication
Are there pulmonary vein geometrical features associated with reconnection after pulsed field ablation of atrial fibrillation? Heart Rhythm. Published 29 July 2025. doi:10.
Summarised from the published abstract; every number is checked against it