Heart failure & cardiomyopathies

Racial Differences in Diabetic Cardiomyopathy: The ARISE-HF Trial

J Am Coll CardiolPublished Secondary analysis of the ARISE-HF randomised trial

Authors' conclusion

Racial and ethnic differences exist in baseline characteristics of persons affected by DbCM, with Black and Hispanic study participants demonstrating higher risk features.

Study context

Population
Persons with diabetic cardiomyopathy (T2DM, structural heart disease, impaired exercise capacity)
Participants
691 persons
Comparison
Baseline characteristics by race and ethnicity

Primary result

As reported in the abstract

baseline
  • Black and Hispanic patients had lower use of DM treatments
  • Black patients had poorer baseline ventricular function and more impaired global longitudinal strain
  • Black patients had poorer health status, more reduced physical activity and greater impairment in exercise capacity on cardiopulmonary exercise testing vs entire cohort
  • Hispanic patients also displayed compromised cardiopulmonary exercise testing functional capacity
  • White patients demonstrated higher physical activity and functional capacity

Further findings

Baseline characteristics, whole cohort

Mean age
67.4 years
Women
50%

Original publication

Racial Differences in Diabetic Cardiomyopathy: The ARISE-HF Trial. J Am Coll Cardiol. Published 16 July 2024. doi:10.1016/j.jacc.2024.04.053

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