Arrhythmia burden in congenitally corrected transposition of the great arteries: Does treatment pathway matter?
Authors' conclusion
Burden and type of arrhythmias in patients with cc-TGA varied on the basis of treatment pathway.
Study context
- Population
- Patients with congenitally corrected transposition of the great arteries (cc-TGA), Cleveland Clinic Children's, 1995–2021
- Participants
- 170 patients
- Exposure
- Anatomic repair vs physiologic repair vs nonsurgical management
- Anatomic repairn = 82
- Physiologic repairn = 46
- Nonsurgical managementn = 42
- Outcome
- Rate of bradyarrhythmias and tachyarrhythmias by treatment pathway
- Follow-up
- Median 11.8 years
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Heart block/permanent pacemaker implantation
P = 0.001
- Heart block/permanent pacemaker implantation, all patients
- 49 (29%)
Observational data: associations, not effects.
Further findings
AF — Physiologic repair, Nonsurgical management vs Anatomic repair
P < 0.0001
Atrial flutter
| Outcome | Anatomic repair | Physiologic repair | Nonsurgical management | P value |
|---|---|---|---|---|
| Freedom from postoperative complete heart block/permanent pacemaker implantation · 5 yearsAnatomic repair vs Physiologic repair | 85% | 68% | — not stated in the abstract | P = 0.02 |
— not stated in the abstract
Tachyarrhythmias
- Tachyarrhythmias, all patients
- 29%
Original publication
Arrhythmia burden in congenitally corrected transposition of the great arteries: Does treatment pathway matter? Heart Rhythm. Published 16 January 2025. doi:10.
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