Pulmonary vascular disease & thromboembolism
Arterial cardiovascular disease risk after venous thromboembolism in young adults: a Danish nationwide cohort study
Authors' conclusion
Young adults with VTE had an elevated risk of CVD compared with persons in an age- and sex-matched comparison cohort.
Study context
- Population
- Young adults (≤40 years) with venous thromboembolism (VTE), Denmark, 1996–2021
- Participants
- 15,810 vs 79,050
- Exposure
- Young adults with VTE vs age- and sex-matched general population comparison cohort
- VTEn = 15,810
- Comparisonn = 79,050reference
- Outcome
- Cardiovascular disease (CVD) (MI and ischemic stroke)
- Follow-up
- 0-1-, 0-5- and 0-10-year windows
Methodological detailsage- and sex-matched (1:5) comparison cohort
- Age- and sex-matched (1:5) comparison cohort
Main finding
As reported in the abstract
VTE vs ComparisonAdjusted hazard ratio (95% CI)
0-1-year window
7.4(4.3–12.8)
0-5-year window
3.8(3.0–4.9)
0-10-year window
3.1(2.6–3.6)
Observational data: associations, not effects.
Further findings
MI and ischemic stroke separately; strata by sex, age, VTE-provoking risk factors, calendar year
- Similar findings
Original publication
Arterial cardiovascular disease risk after venous thromboembolism in young adults: a Danish nationwide cohort study. Eur J Prev Cardiol. Published 22 November 2025. doi:10.
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