Arrhythmias & electrophysiology
Assessing left atrial intramyocardial fat infiltration from computerized tomography angiography in patients with atrial fibrillation
Authors' conclusion
Persistent forms of AF are associated with greater degree of LA intramyocardial adipose infiltration, independently of body mass index. Compared to controls, AF patients present higher LA inFAT volume at left and right superior pulmonary vein antra.
Study context
- Population
- Patients with atrial fibrillation (AF) diagnosis undergoing multi-detector computer tomography (MDCT), compared with age-matched controls60 AF patients + 20 controls
- Participants
- 30 / 30 / 20
- Exposure
- Persistent AF vs paroxysmal AF vs controls without AF history
- Persistent AFn = 30
- Paroxysmal AFn = 30
- Controlsn = 20reference
- Outcome
- LA infiltrated adipose tissue (inFAT) volume from MDCT-derived 3D fat infiltration maps
Methodological detailsconsecutive patients, age-matched controls
- Consecutive patients
- Age-matched controls
Main finding
As reported in the abstract
LA inFAT volume
- Infiltrated adipose tissue (inFAT) volume significantly different across the three groups
- P = 0.009
Observational data: associations, not effects.
Further findings
Dense inFAT, corrected for BMI
- Significant difference retained after correcting for BMI
- P = 0.028
inFAT radiodensity
- More negative inFAT radiodensity values in AF patients
Regional distribution of left atrial (LA) inFAT
- Significantly higher LA inFAT at left and right superior pulmonary vein antra in AF patients
Original publication
Assessing left atrial intramyocardial fat infiltration from computerized tomography angiography in patients with atrial fibrillation. Europace. Published 27 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →