Arrhythmias & electrophysiology
Complex repolarization dynamics in ex vivo human ventricles are independent of the restitution properties
Authors' conclusion
We present evidence of complex higher-order periodicities and the co-existence of such regions with stable non-chaotic areas in ex vivo human hearts.
Study context
- Population
- Explanted human hearts from heart transplant recipients (RV endocardial surface, rapid pacing)
- Participants
- 6 explanted hearts
- Outcome
- Existence of higher-order periodicities in repolarization (periods over two)
Methodological detailsex vivo optical mapping
- Ex vivo optical mapping
Main finding
As reported in the abstract
- Statistically significant global 1:4 peak
- 3 of 6 hearts
- Regional presence of periods >2 (spatially heterogeneous Periods 4, 6 and 8)
- all hearts
Original publication
Complex repolarization dynamics in ex vivo human ventricles are independent of the restitution properties. Europace. Published 25 November 2023. doi:10.
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