Association Between Air Pollution and Monday Peak Mortality From Acute Myocardial Infarction
Authors' conclusion
Our results suggest that the excess AMI mortality observed on Mondays in the Spanish population is not explained by concurrent variations in major air pollutants.
Study context
- Population
- Acute myocardial infarction (AMI) deaths in mainland Spain and the Balearic Islands, 2004–2018
- Participants
- 260,320 AMI deaths
- Comparison
- Air pollution levels and inter-day changes vs Monday excess AMI mortality
- Outcome
- Association between air pollution (PM2.5, PM10, nitrogen dioxide, ozone) and the Monday excess in AMI mortality
Methodological detailsmultilevel meta-analysis
- Multilevel meta-analysis
Pooled result
As reported in the abstract
- No association between air pollution and the Monday peak in AMI mortality
- Intra-weekly pattern in AMI mortality not modified by absolute level or inter-day change in air pollutants (after adjustment for inter-weekly baseline mortality changes)
Further pooled results
Weekly variation in AMI mortality
- Monday peak above the weekly average
- +3.7%
Sunday-to-Monday increase in particulate air pollution
- PM2.5 increase
- 12.6%
- PM10 increase
- 12.0%
- No significant increase between other weekdays
- Lower particulate levels on weekends than weekdays
Original publication
Association Between Air Pollution and Monday Peak Mortality From Acute Myocardial Infarction. JACC Adv. Published 17 December 2025. doi:10. 1016/ j. jacadv. 2025. 102378
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