Association Between Appendicular Skeletal Muscle Mass and Myocardial Glucose Uptake Measured by 18F-FDG PET
Authors' conclusion
In men, ASM was strongly associated with myocardial glucose uptake as measured by 18F-FDG PET/CT. In women, age was significantly correlated with myocardial substrate utilization, but not with ASM.
Study context
- Population
- Individuals examined at the Severance Health Check-up Center, January 2018–February 2019
- Participants
- 299 individuals
- Exposure
- ASM/Ht2 and myocardial glucose uptake, by sex
- Menn = 182
- Womenn = 117
- Outcome
- Myocardial glucose uptake by 18F-FDG PET/CT [ln (SUVheart/liver)] in relation to ASM/Ht2
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Correlation of ASM/Ht2 with myocardial glucose uptake
| Group | R | P | Adjusted standardized β | Adjusted P | Adjusted β |
|---|---|---|---|---|---|
| Men | 0.154 | P = 0.038 | 0.397 | P = 0.004 | |
| Women | −0.042 | P = 0.652 | P = 0.698 | - 0.051 |
R
Men0.154
Women−0.042
P
MenP = 0.038
WomenP = 0.652
Adjusted standardized β
Men0.397
Women— not stated in the abstract
Adjusted P
MenP = 0.004
WomenP = 0.698
Adjusted β
Men— not stated in the abstract
Women- 0.051
Observational data: associations, not effects.
Further findings
- Age as determinant of myocardial glucose uptake (Women)
- −0.424 · β · P P=0.029
Original publication
Association Between Appendicular Skeletal Muscle Mass and Myocardial Glucose Uptake Measured by 18F-FDG PET. ESC Heart Fail. Published 30 September 2024. doi:10.
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