Prevention & lipids

Automated Breast Arterial Calcification Score Is Associated With Cardiovascular Outcomes and Mortality

JACC AdvPublished Retrospective cohort study

Authors' conclusion

BAC is independently associated with mortality and CVD, especially among younger women.

Study context

Population
Women with a screening mammogram, 2007–2016
Participants
18,092 women
Exposure
Breast arterial calcification (BAC) vs no BAC on screening mammogram
Outcome
Mortality and composite of acute MI, HF, stroke and mortality
Follow-up
Median 6 years
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

BAC

Death
7.8%
Composite
12.4%

No BAC

Death
2.3%
Composite
4.3%

Death

BAC7.8%
No BAC2.3%

Composite

BAC12.4%
No BAC4.3%
BAC vs No BACAdjusted hazard ratio (95% CI)
Mortality
1.49(1.33–1.67)
Composite
1.56(1.41–1.72)

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)
Per 10-point increase in BAC scorePer 10-point BAC score increase · mortality1.08 (1.06–1.11)
Per 10-point increase in BAC scorePer 10-point BAC score increase · composite1.08 (1.06–1.10)

Younger women (subgroup)

BAC especially predictive of future events among younger women

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Automated Breast Arterial Calcification Score Is Associated With Cardiovascular Outcomes and Mortality. JACC Adv. Published 27 September 2024. doi:10.1016/j.jacadv.2024.101283

Composed by AI from the published abstract and checked against it. How Briefs are made →

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