Acute cardiac care & resuscitation
Association between body mass index and survival outcomes for in-hospital cardiac arrest
Authors' conclusion
For patients with IHCA, underweight patients had lower rates of survival and favorable neurological survival, regardless of initial cardiac arrest rhythm. In contrast, overweight and obese patients had better outcomes only when the initial rhythm was shockable.
Study context
- Population
- In-hospital cardiac arrest (IHCA) patients with body mass index (BMI) data during 2006–2012IHCA patients with BMI data · shockable rhythm 10,219 · non-shockable arrest rhythm 46,192
- Participants
- 56,411 patients
- Comparison
- Association between BMI and favorable neurological survival (discharge cerebral performance category score of 1) and survival to discharge
- Outcome
- Favorable neurological survival, shockable rhythm
- Follow-up
- Discharge
Methodological detailsGet With The Guidelines®-Resuscitation
- Get With The Guidelines®-Resuscitation
Main finding
As reported in the abstract
Each group vs normalOdds ratio (95% CI)
UnderweightAfter adjustment
0.64(0.49–0.84)
OverweightAfter adjustment
1.17(1.04–1.33)
ObeseAfter adjustment
1.16(1.00–1.34)
Very obese
1.06(0.91–1.24)
- Of 10,219 patients with a shockable rhythm, had favorable neurological survival
- 3014 (29.4%)
Further findings
| Outcome | OR (CI) | |
|---|---|---|
| Favorable neurological survival and survival to discharge, non-shockable rhythmUnderweightvs normalFavorable neurological survival, after adjustment | 0.76 (0.66–0.89) | |
| Favorable neurological survival and survival to discharge, non-shockable rhythmUnderweightvs normalSurvival to discharge, after adjustment | 0.85 (0.75–0.95) | |
| 0.512Odds ratio (log scale) |
- Favorable neurological survival and survival to discharge, non-shockable rhythm — of 46,192 patients with a non-shockable arrest rhythm, had favorable neurological survival
- 4844 (10.4%)
- Favorable neurological survival and survival to discharge, non-shockable rhythm — of 46,192 patients with a non-shockable arrest rhythm, survived to discharge
- 7,331 (15.8%)
Survival to discharge, shockable rhythm
- Of 10,219 patients with a shockable rhythm, survived to discharge
- 3,964 (38.7%)
- A similar pattern was observed for survival to discharge
Favorable neurological survival and survival to discharge, non-shockable rhythm
- All other BMI groups had similar rates
Original publication
Association between body mass index and survival outcomes for in-hospital cardiac arrest. Resuscitation. Published 9 June 2025. doi:10.
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