Heart failure & cardiomyopathies
Association Between Cardio-Ankle Vascular Index and Heart Failure Outcomes: Insights From a Prospective Multicenter Cohort
Primary result · HF-related hospitalizations and CV deathResult — go to the resultHazard ratio 3.18 95% CI 1.09–9.31Authors' conclusion
In this exploratory study, elevated CAVI was associated with HF-related hospitalizations and cardiovascular death and modestly improved the risk prediction beyond conventional risk factors.
Study context
- Population
- Japanese adults aged 40 to 74 years with CV risk factors
- Participants
- 2,932 adults
- Comparison
- High cardio-ankle vascular index (CAVI) vs lower CAVI
- Primary endpoint
- Heart failure (HF)-related hospitalizations and CV death
- Follow-up
- Median 4.9 years
Methodological detailsmulticentre, exploratory
- Multicentre
- Exploratory
Primary result
As reported in the abstract
Hazard ratio
3.18
95% CI 1.09–9.31
P = 0.034
High CAVIvs Lower CAVI
HR 3.18 (95% CI 1.09–9.31); P = 0.034
- Primary outcomes recorded (overall)
- 32 patients (1.1%)
Further findings
Incremental prognostic value of adding CAVI to conventional risk model
- Global chi value increased from 8.82 to 18.77
- P = 0.002
- Net reclassification index 0.621
- P < 0.001
Original publication
Association Between Cardio-Ankle Vascular Index and Heart Failure Outcomes: Insights From a Prospective Multicenter Cohort. JACC Adv. Published 29 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →