Arrhythmias & electrophysiology
Association between catheter ablation of atrial fibrillation and mortality or stroke
Main finding · All-cause mortality or strokeResult — go to the resultHazard ratio 0.58 95% CI 0.48–0.69Authors' conclusion
Catheter ablation of atrial fibrillation was associated with a reduction in the primary endpoint of all-cause mortality or stroke. This result was driven by a marked reduction in all-cause mortality.
Study context
- Population
- Patients with AF, Swedenmatched cohorts n=3955 each
- Participants
- 5,628 vs 48,676
- Exposure
- Catheter ablation vs medical management of AF
- Catheter ablationn = 5,628
- Controln = 48,676reference
- Outcome
- Composite of:
- All-cause mortality
- Stroke
- Follow-up
- Mean 4.5±2.8 years
Methodological detailspropensity-score matched, 3 Swedish electrophysiology units
- Propensity-score matched
- 3 Swedish electrophysiology units
Main finding
All-cause mortality or stroke
Hazard ratio
0.58
95% CI 0.48–0.69
Catheter ablationvs Control
HR 0.58 (95% CI 0.48–0.69)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| All-cause mortality | 0.51 (0.41–0.63) | |
| StrokeTrend in favour of catheter ablation | 0.75 (0.53–1.07) | |
| 0.512Hazard ratio (log scale) |
Baseline differences (before matching) Catheter ablation mean 1.4 (SD 1.4) · Control mean 1.6 (SD 1.5)
CHA2DS2-VASc Catheter ablation 1.4±1.4 · Control 1.6±1.5
Median income Catheter ablation 288 KSEK/year · Control 212 KSEK/year
University education
- Baseline differences (before matching): all p<0.001
Original publication
Association between catheter ablation of atrial fibrillation and mortality or stroke. Heart. Published 1 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →