Arrhythmias & electrophysiology
Association Between Diagnosis-to-Ablation Time and Postablation Outcomes in Older Patients With Persistent Atrial Fibrillation
Corrected 23 Oct 2026: Measure wording clarified; no values changed.
Authors' conclusion
In older patients with persistent AF, a DAT ≤12 months was associated with lower AA recurrence and lower risk of adverse cardiovascular outcomes
Study context
- Population
- Older patients with persistent atrial fibrillation (AF) undergoing catheter ablation, January 2020 to December 2022560 analysed
- Participants
- 587 patients
- Exposure
- Early vs late catheter ablation
- Early ablationn = 332
- Late ablationn = 255reference
- Outcome
- Freedom from atrial arrhythmia (AA) recurrence
- Follow-up
- 24 months
Main finding
Freedom from AA recurrence
Hazard ratio
0.68
95% CI 0.52–0.91, event not clearly stated
P = 0.005
Events by group
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Composite outcome (death, CV hospitalization, ischemic stroke) · 24 months | 1.70 (1.23–2.34) | P = 0.001 | |
| CV hospitalization · 24 months | 1.57 (1.10–2.26) | P = 0.011 | |
| Ischemic stroke | 1.87 (0.83–4.19) | P = 0.126 | |
| Death | 2.20 (0.54–8.93) | P = 0.267 | |
| 0.10.31310Hazard ratio (log scale) |
Original publication
Association Between Diagnosis-to-Ablation Time and Postablation Outcomes in Older Patients With Persistent Atrial Fibrillation. JACC Adv. Published 22 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →