Valvular & structural heart disease
Association Between Functional Tricuspid Regurgitation and Mortality Following Cardiac Surgery
Main finding · Mid-term mortalityResult — go to the resultHazard ratio 2.58 95% CI 1.22–5.47Authors' conclusion
In this diverse cohort of contemporary cardiac surgery patients, moderate functional TR was associated with increased mortality and major morbidity, particularly in the absence of pulmonary hypertension.
Study context
- Population
- Patients undergoing CABG, aortic or mitral valve surgery, without severe tricuspid regurgitation (TR), organic tricuspid valve pathology or tricuspid valve surgery238 deaths
- Participants
- 2,119 patients
- Exposure
- Moderate, mild, trivial vs absent functional TR
- Moderate TRn = 185
- Mild TRn = 636
- Trivial TRn = 1,126
- Absent TRn = 172reference
- Outcome
- Mid-term mortality
- Follow-up
- Median 2.6 years
Methodological detailsexternal validation cohort
- External validation cohort
Main finding
As reported in the abstract
Hazard ratio
2.58
95% CI 1.22–5.47
Moderate TRvs Absent TR
HR 2.58 (95% CI 1.22–5.47)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| In-hospital mortality or major morbidityModerate TRvs Absent TRAdjusted | 3.18 (1.37–7.42) | |
| 0.10.31310Odds ratio (log scale) |
Mortality, by preoperative pulmonary artery systolic pressure (subgroup)
- Association between TR and mortality apparent with PASP <40 mm Hg but not ≥40 mm Hg
- P for interaction = 0.036
Original publication
Association Between Functional Tricuspid Regurgitation and Mortality Following Cardiac Surgery. JACC Adv. Published 1 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →