Heart failure & cardiomyopathies

Association Between Haemoglobin, Albumin, Lymphocytes, and Platelets and Mortality in Patients with Heart Failure

ESC Heart FailPublished Retrospective cohort study

Authors' conclusion

HALP may be a potential marker for predicting mortality in patients with heart failure.

Study context

Population
Adults hospitalised with HF, 2019–2021
Participants
730 adults
Exposure
Haemoglobin, albumin, lymphocytes, and platelets (HALP) score and mortality
Outcome
1-month mortality and 1-year mortality
Follow-up
1 month and 1 year

Main finding

As reported in the abstract

High HALP scoresOdds ratio (95% CI)P value
1-month mortality
0.978(0.963–0.992)
P = 0.003
1-year mortality
0.987(0.977–0.997)
P = 0.009
Died within 1 month
61 (8.36%)
Died within 1 year
77 (10.55%)

Observational data: associations, not effects.

Further findings

1-year mortality, by NYHA stage and left ventricular ejection fraction (LVEF) (subgroups)

OR (95% CI)P value
High HALP scoresNYHA stage II/III0.978 (0.957–1.000)P = 0.045
High HALP scoresLVEF ≥50%0.970 (0.945–0.996)P = 0.024
Prediction of 1-year mortality (AUC)
AUC
HALP
0.677(95% CI: 0.619-0.735)
PNI
0.666(95% CI: 0.608-0.723)
CRP
0.638(95% CI: 0.572-0.704)
MAGGIC-HF
0.654(95% CI: 0.591-0.717)

Original publication

Association Between Haemoglobin, Albumin, Lymphocytes, and Platelets and Mortality in Patients with Heart Failure. ESC Heart Fail. Published 19 January 2024. doi:10.1002/ehf2.14662

Composed by AI from the published abstract and checked against it. How Briefs are made →

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