Acute cardiac care & resuscitation
Association between increasing institutional experience with ECPR and outcomes in patients with out-of-hospital cardiac arrest: A nationwide multicenter observational study in Japan (the JAAM–out-of-hospital cardiac arrest (OHCA) registry)
Authors' conclusion
Increasing institutional experience of ECPR did not significantly improve 30-day survival after OHCA but was associated with a shorter interval between hospital arrival and initiation of ECMO. In patients with non-shockable OHCA, increasing experience of ECPR improved 30-day survival. (246/250 words).
Study context
- Population
- Patients with OHCA in Japan, June 2014 to December 2020, who were in cardiac arrest on hospital arrival and treated with extracorporeal membrane oxygenation (ECMO)patients treated with ECPR at any of 87 facilities · shockable rhythm on admission 1,047 · non-shockable rhythm on admission 1,268
- Participants
- 2,315 patients
- Exposure
- Association between institutional experience with extracorporeal cardiopulmonary resuscitation (ECPR) and outcomes after out-of-hospital cardiac arrest (OHCA)
- Outcome
- 30-day survival
- Follow-up
- 30 days
Methodological detailsJAAM-OHCA registry
- JAAM-OHCA registry
Main finding
As reported in the abstract
- 30-day survival rate was not significantly associated with the accumulated case volume of ECPR
Observational data: associations, not effects.
Secondary outcomes
Interval between hospital arrival and initiation of ECMO (secondary outcome)
- Decreased significantly with increasing experience of ECPR
- P < 0.001
- Jonckheere-Terpstra test
30-day survival in non-shockable cases (subgroup)
- Tended to improve with increasing experience of ECPR
- P = 0.04
- Cochran-Armitage trend test
Original publication
Association between increasing institutional experience with ECPR and outcomes in patients with out-of-hospital cardiac arrest: A nationwide multicenter observational study in Japan (the JAAM–OHCA registry). Resuscitation. Published 3 January 2025. doi:10.
Summarised from the published abstract; every number is checked against it