Meta-analysis
Association between long-term aircraft noise exposure and cardiovascular disease: a meta-analysis with focused subgroup analyses
- Systematic review and meta-analysis
- random-effects model
- pre-registered protocol
Authors' conclusion
Our study demonstrates a significant association between aircraft noise exposure and increased risk of cardiovascular events and mortality, with stronger association during night-time exposure.
Study context
- Population
- Adults aged 18 years and older exposed to long-term aircraft noise; follow-up 1 to 20 years
- Participants
- ∼35.5 million adults · 34 studies
- Comparison
- Aircraft noise exposure vs lower/no exposure
- Outcome
- CVD risk
Pooled result
As reported in the abstract
Aircraft noise exposure and cardiovascular disease (CVD) risk, OR 1.1 (95% CI 1.07-1.14)
P < 0.001
Further pooled results
CVD risk, night-time exposure (subgroup)
- Night-time exposure and CVD risk, OR 1.14 (95% CI 1.04-1.26)
- P = 0.006
Overall CVD mortality
- Aircraft noise exposure and CVD mortality, OR 1.07 (95% CI 1.01-1.13)
- P = 0.02
- Association appeared stronger in females; sex-specific difference not statistically significant
MI-related mortality
- Aircraft noise exposure and MI mortality, OR 1.07 (95% CI 1.02-1.12)
- P = 0.009
Ischaemic heart disease (IHD) and stroke mortality
- IHD mortality, OR 1.05, not significant
- P = 0.08
- Stroke mortality, OR 1.01, not significant
- P = 0.3
Hypertension
- Overall hypertension, OR 1.02, not significant
- P = 0.74
- Hypertension in males, OR
- 1.42
- Hypertension in females, OR
- 1.01
SBP
- Aircraft noise exposure and SBP, MD 1.83 mmHg
- P = 0.04
Original publication
Association between long-term aircraft noise exposure and cardiovascular disease: a meta-analysis with focused subgroup analyses. Eur J Prev Cardiol. Published 31 July 2025. doi:10.1093/eurjpc/zwaf471
Summarised from the published abstract; every number is checked against it