Acute cardiac care & resuscitation
Association Between Pressure-Adjusted Heart Rate and In-Hospital Mortality in Cardiogenic Shock
Main finding · In-hospital mortality per 10-unit higher PAHRResult — go to the resultAdjusted odds ratio 1.35 95% CI 1.15–1.58Authors' conclusion
PAHR, a simple hemodynamic index calculated from vital signs and central venous pressure, is strongly associated with in-hospital mortality in CS.
Study context
- Population
- Cardiogenic shock (CS) admissions (2018–2023) with invasive hemodynamic assessment within 24 hours of cardiac ICU admission; concurrent mechanical circulatory support excluded in the primary analysis
- Participants
- 1,411 CS admissions
- Exposure
- Higher vs lower pressure-adjusted heart rate
- Outcome
- In-hospital mortality per 10-unit higher PAHR
Methodological detailsmultinational registry, cardiac ICUs
- Multinational registry
- Cardiac ICUs
Main finding
As reported in the abstract
Adjusted odds ratio
1.35
95% CI 1.15–1.58
PAHR per 10 units
adjusted OR 1.35 (95% CI 1.15–1.58)
Per 10 units, as printed
Observational data: associations, not effects.
Further findings
Baseline hemodynamics
- Median heart rate (beats/min)
- 92
- Median right atrial pressure (RAP) (mm Hg)
- 15
- Median mean arterial pressure (MAP) (mm Hg)
- 75
- Median pressure-adjusted heart rate (PAHR)
- 17
- Receiving vasoactive support
- 75%
- Acute MI
- 18%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association Between Pressure-Adjusted Heart Rate and In-Hospital Mortality in Cardiogenic Shock. JACC Adv. Published October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →