Heart failure & cardiomyopathies

Association Between White Blood Cell-to-Haemoglobin Ratio and 30 Day Mortality in Heart Failure in Intensive Care Unit

ESC Heart FailPublished Retrospective cohort study

Main finding · 30 day mortalityResult — go to the resultHazard ratio 1.16 95% CI 1.07–1.27

Authors' conclusion

WHR was positively associated with and performed well to predict 30 day mortality

Study context

Population
Heart failure (HF) patients admitted to the intensive care unit (ICU) (MIMIC-III 2001–12 and MIMIC-IV 2008–19 databases)
Participants
13,702 patients
Exposure
High vs low white blood cell-to-haemoglobin ratio
Outcome
30 day mortality from ICU admission
Follow-up
30 days

Main finding

30 day mortality

Hazard ratio

1.16

95% CI 1.07–1.27

P < 0.001

High WHRvs Low WHR
HR 1.16 (95% CI 1.07–1.27); P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

Prediction of 30 day mortality by WHR

AUC of WHR
0.751 (95% CI 0.746-0.756)

Original publication

Association Between White Blood Cell-to-Haemoglobin Ratio and 30 Day Mortality in Heart Failure in Intensive Care Unit. ESC Heart Fail. Published 28 November 2023. doi:10.1002/ehf2.14592

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