Association of accelerometer-derived physical activity with all-cause and cause-specific mortality among individuals with cardiovascular diseases: a prospective cohort study
Authors' conclusion
We found an inverse non-linear association between all intensities of PA (LPA, MPA, VPA, and MVPA) and mortality risk in CVD patients using accelerometer-derived data, but with a larger magnitude of the associations than that in previous studies based on self-reported PA.
Study context
- Population
- Individuals with pre-existing cardiovascular disease (CVD) from the UK Biobank (mean age 66.6 years, 34.1% female)691 deaths
- Participants
- 8,024 individuals
- Exposure
- Highest vs lowest quartile of accelerometer-measured physical activity (PA) by intensity
- Outcome
- All-cause mortality (also cancer and CVD mortality)
- Follow-up
- Median 6.8 years
Methodological detailsUK Biobank, wrist-worn accelerometers
- UK Biobank
- Wrist-worn accelerometers
Main finding
As reported in the abstract
All-cause mortality, highest quartile of PA
Hazard ratio (95% CI)
Highest quartile LPAlight-intensity PA
0.63(0.51–0.79)
Highest quartile MPAmoderate-intensity PA
0.42(0.33–0.54)
Highest quartile VPAvigorous-intensity PA
0.47(0.37–0.60)
min/week
- HR plateau, LPA
- 1800
- HR plateau, MPA
- 320
- HR plateau, VPA
- 15
Observational data: associations, not effects.
Further findings
Cancer and CVD mortality
- Deaths from cancer
- 273
- Deaths from CVD
- 219
- Similar associations observed for cancer and CVD mortality
Population-attributable fractions
- Highest population-attributable fractions (PAFs) for VPA, followed by MPA
Original publication
Association of accelerometer-derived physical activity with all-cause and cause-specific mortality among individuals with cardiovascular diseases: a prospective cohort study. Eur J Prev Cardiol. Published 1 August 2024. doi:10.
Summarised from the published abstract; every number is checked against it