Heart failure & cardiomyopathies
Association of sex with in-hospital management and outcomes of patients with heart failure: Data from the REAL-HF registry
Authors' conclusion
Finally, female sex was not associated with worse clinical outcomes.
Study context
- Population
- Adults hospitalised for HF in 2020 to 2021 (REAL-HF registry)
- Participants
- 4,016 adults
- Exposure
- Women vs men
- Womenn = 1,818
- Outcome
- In-hospital management and outcomes (readmissions, mortality)
Methodological detailsmulticentre, national registry
- Multicentre
- National registry
Main finding
As reported in the abstract
SexOdds ratio (95% CI)P value
30-day readmission
0.89(0.71–1.11)
P = 0.3041-year readmission
1.02(0.88–1.19)
P = 0.777In-hospital mortality
1.14(0.73–1.78)
P = 0.5581-year mortality
1.08(0.87–1.33)
P = 0.478Observational data: associations, not effects.
Further findings
GDMT at discharge (HFrEF subgroup, n=1525)
P = 0.197
Hospitalisation ward
Internal medicine
Specialised cardiology units
Baseline profile
Age Women 83 years · Men 77 years
Arterial hypertension
HFpEF
- Baseline profile: Age P < .0001
- Baseline profile: Hypertension P = .011
- Baseline profile: HFpEF P < .001
Outcomes by LVEF-based HF category
- Similar results across HF categories by LVEF
Original publication
Association of sex with in-hospital management and outcomes of patients with heart failure: Data from the REAL-HF registry. Am Heart J. Published 27 August 2024. doi:10.
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