Heart failure & cardiomyopathies
Association of Tricuspid Regurgitation With Outcome in Acute Heart Failure
Authors' conclusion
In patients hospitalized for acute HF, the severity of TR is associated with 1-year survival, regardless of the presence of PH. The coexistence of moderate-severe TR and estimated PH was associated with a further increase in mortality risk.
Study context
- Population
- Patients admitted for acute heart failure (HF) with noninvasive estimation of tricuspid regurgitation (TR) and pulmonary arterial systolic pressure
- Participants
- 1,176 patients
- Exposure
- Moderate-severe TR vs no/mild TR
- Moderate-severe TRn = 352
- Outcome
- All-cause mortality
- Follow-up
- 1 year
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
1-year mortality
Hazard ratio
1.718
P = 0.009
adjusted for echocardiographic parameters
Hazard ratio
1.761
P = 0.024
adjusted additionally for clinical variables
- Overall 1-year deaths
- 184 (15.6%)
Observational data: associations, not effects.
Further findings
| Outcome | HR | P value |
|---|---|---|
| 1-year mortality, coexistent moderate-severe TR and PH vs no TR or PH | 3.024 | P < 0.001 |
1-year mortality by pulmonary hypertension (PH), RV dysfunction and LVEF <50% (subgroups)
- Association of moderate-severe TR with outcome consistent with vs without PH, RV dysfunction and LVEF <50%
Original publication
Association of Tricuspid Regurgitation With Outcome in Acute Heart Failure. Circ Cardiovasc Imaging. Published 29 June 2023. doi:10.
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