Associations Between Physical Activity Patterns and Cardiovascular Events and Risk Factors: Cross-Sectional and Prospective Studies
Authors' conclusion
In a population-based study, we observed a higher risk for cardiovascular events in participants whose daily PA occurred predominantly in the early morning (7 am-12 am) or was evenly distributed throughout the day. No PA pattern was consistently associated with hypertension, blood lipids, or diabetes markers.
Study context
- Population
- Participants of the CoLaus-PsyCoLaus study, Lausanne, Switzerland; S1: 55.3% females, mean age 61.2 ± 9.7 years; S2: 54.3% females, 64.4 ± 9.5 yearsS1 2,465
- Exposure
- Physical activity (PA) timing patterns
- Outcome
- Cardiovascular disease (CVD) events and CVD risk factors
Methodological detailsaccelerometer-assessed PA, K-means clustering
- Accelerometer-assessed PA
- K-means clustering
Main finding
As reported in the abstract
CVD events
Hazard ratio (95% CI)
Morning PA
3.33(1.08–10.3)
Evenly distributed daily PA
3.16(1.04–9.57)
Observational data: associations, not effects.
Further findings
Hypertension (S1)
| OR (95% CI) | ||
|---|---|---|
| Morning PAMultivariable-adjusted; similar trend in S2 | 1.36 (1.00–1.84) | |
| 0.512Odds ratio (log scale) |
| Outcome | Estimate |
|---|---|
| Hypolipidemic drug treatment (S2) | 1.88 (CI 1.07–3.30) |
| DM (S2)Similar trend in S1 | 1.82 (95% CI 1.06–3.12) |
Total, HDL-, LDL-cholesterol, TG
- No significant association with PA clusters
Original publication
Associations Between Physical Activity Patterns and Cardiovascular Events and Risk Factors: Cross-Sectional and Prospective Studies. JACC Adv. Published 9 October 2024. doi:10.
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