Cardio-oncology & otherCohort study
Associations between social determinants of health and cardiovascular and cancer mortality in cancer survivors: a prospective cohort study
- Prospective cohort study
Cause-specific multivariable Cox regression; cancer survivors and individuals without cancer modelled separately
Authors' conclusion
Social determinants of health were independently associated with all-cause, cardiovascular, and cancer mortality among cancer survivors but not among individuals without cancer.
Study context
- Population
- Adults in the 2013–2017 National Health Interview Survey, cancer survivors and individuals without canceranalysed
- Participants
- 37,882 adults
- Exposure
- Worse vs better social determinants of health (SDOH)
- Cancer survivorsn = 4,179
- Individuals without cancern = 33,703
- Outcome
- CV mortality
Main finding
CV mortality, cancer survivors
Adjusted hazard ratio
1.31
CI 1.02–1.68
Worse vs better SDOH (38-point, 6-domain deprivation score)
aHR 1.31 (CI 1.02–1.68)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Cancer mortality
| Comparison | aHR (CI) | |
|---|---|---|
| Worse SDOH · cancer survivors | 1.20 (1.01–1.42) | |
| 0.512Adjusted hazard ratio (log scale) |
All-cause mortality
| Comparison | aHR (CI) | |
|---|---|---|
| Worse SDOH · cancer survivors | 1.16 (1.02–1.31) | |
| 0.512Adjusted hazard ratio (log scale) |
Cancer mortality
- Individuals without cancer: no association between SDOH and cancer mortality
All-cause mortality
- Individuals without cancer: associated when adjusted for demographics only, not after further adjustment
SDOH domains, cancer survivors (post hoc)
- Psychological distress, economic stability, neighbourhood, physical environment and social cohesion, and food insecurity variably associated with outcomes
- post hoc
Original publication
Associations between social determinants of health and cardiovascular and cancer mortality in cancer survivors: a prospective cohort study. Eur J Prev Cardiol. Published 30 October 2024. doi:10.1093/eurjpc/zwae318
Summarised from the published abstract; every number is checked against it