Acute cardiac care & resuscitation

Associations of manual defibrillator compared to automated external defibrillator usage with defibrillation and resuscitation quality during in-hospital cardiac arrest

ResuscitationPublished multicenter cohort study

Main finding · Difference in accuracy of rhythm analysesResult — go to the resultAdjusted odds ratio 0.5 95% CI 0.2–1.3

Authors' conclusion

Using manual defibrillators compared to AEDs was not associated with a higher accuracy of rhythm analyses, but with shorter chest compression pause durations for rhythm analysis and shorter peri-shock pauses.

Study context

Population
In-hospital cardiac arrest in the Central Denmark Region between April 2019 and March 2024cardiac arrests analysed, 1715 rhythm analyses from manual defibrillators and 602 AED analyses
Participants
529 participants
Exposure
Manual defibrillator and AED usage during in-hospital cardiac arrest (IHCA)
  • Manual defibrillatorn = 1,715
  • AEDn = 602reference
Outcome
Difference in accuracy of rhythm analyses

Main finding

As reported in the abstract

Adjusted odds ratio

0.5

95% CI 0.2–1.3

Manual defibrillator vs AED
adjusted odds ratio 0.5 (95% CI 0.2–1.3)

Observational data: associations, not effects.

Secondary outcomes

OutcomeDifference (s) (95% CI)
Chest compression pause duration for rhythm analysisShorter with manual defibrillator3.2 (1.7–4.9)
Peri-shock pausesShorter with manual defibrillator7.9 (5.9–9.9)

Original publication

Associations of manual defibrillator compared to automated external defibrillator usage with defibrillation and resuscitation quality during in-hospital cardiac arrest. Resuscitation. Published 23 April 2025. doi:10.1016/j.resuscitation.2025.110619

Summarised from the published abstract; every number is checked against it

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