Acute cardiac care & resuscitation

Associations with resolution of ST-segment elevation myocardial infarction criteria on out-of-hospital 12-lead electrocardiograms following resuscitation from cardiac arrest

ResuscitationPublished secondary analysis of a previous retrospective study

Authors' conclusion

ROSC patients with STEMI on out-of-hospital ECG commonly resolve in the ED (67%). These identified associations may better inform clinical decision making. Post-ROSC out-of-hospital 12-lead ECGs should be repeated on arrival in the ED.

Study context

Population
Adults (≥18 years) with return of spontaneous circulation (ROSC) following out-of-hospital cardiac arrest (OHCA), at least 1 out-of-hospital and emergency department (ED) ECG and transport to the study hospitalpatients entered, 49 had out-of-hospital electrocardiograms (ECGs) diagnostic for STEMI
Participants
176 adults
Comparison
Associations with resolution of STEMI on ED ECG
  • Resolved STEMIn = 33

Primary result

As reported in the abstract

Resolution of out-of-hospital STEMI upon ED evaluation

Resolved STEMI

67%

33/49 of 33

Further findings

OutcomeEstimateP value
Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · shorter with resolutionresuscitation time 13 [interquartile range 5-18] vs 21 [14-28] minutesP = 0.007
Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · less with resolutionepinephrine 3 [1-4] vs 5 [2-10] milligramsP = 0.018
Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · lower with resolutionincidence of norepinephrine 5/33 (15%) vs 11/16 (69%)P ≤ 0.001
Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · less with resolutiontime from ROSC to out-of-hospital ECG acquisition 5.5 [1-8] vs 8.5 [7-14] minutesP = 0.044
Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · more with resolutiontime between out-of-hospital and ED ECG acquisition 34 [25-52] vs 21 [14-27] minutesP = 0.001

Ischemia on ED ECG in patients with non-STEMI out-of-hospital ECGs

More defibrillations were associated with increased ischemia on ED ECG

Original publication

Associations with resolution of ST-segment elevation myocardial infarction criteria on out-of-hospital 12-lead electrocardiograms following resuscitation from cardiac arrest. Resuscitation. Published 6 March 2025. doi:10.1016/j.resuscitation.2025.110567

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