Acute cardiac care & resuscitation
Associations with resolution of ST-segment elevation myocardial infarction criteria on out-of-hospital 12-lead electrocardiograms following resuscitation from cardiac arrest
Authors' conclusion
ROSC patients with STEMI on out-of-hospital ECG commonly resolve in the ED (67%). These identified associations may better inform clinical decision making. Post-ROSC out-of-hospital 12-lead ECGs should be repeated on arrival in the ED.
Study context
- Population
- Adults (≥18 years) with return of spontaneous circulation (ROSC) following out-of-hospital cardiac arrest (OHCA), at least 1 out-of-hospital and emergency department (ED) ECG and transport to the study hospitalpatients entered, 49 had out-of-hospital electrocardiograms (ECGs) diagnostic for STEMI
- Participants
- 176 adults
- Comparison
- Associations with resolution of STEMI on ED ECG
- Resolved STEMIn = 33
Primary result
As reported in the abstract
Resolution of out-of-hospital STEMI upon ED evaluation
Resolved STEMI
67%
33/49 of 33
Further findings
| Outcome | Estimate | P value |
|---|---|---|
| Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · shorter with resolution | resuscitation time 13 [interquartile range 5-18] vs 21 [14-28] minutes | P = 0.007 |
| Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · less with resolution | epinephrine 3 [1-4] vs 5 [2-10] milligrams | P = 0.018 |
| Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · lower with resolution | incidence of norepinephrine 5/33 (15%) vs 11/16 (69%) | P ≤ 0.001 |
| Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · less with resolution | time from ROSC to out-of-hospital ECG acquisition 5.5 [1-8] vs 8.5 [7-14] minutes | P = 0.044 |
| Factors associated with resolution of out-of-hospital STEMI on ED evaluation (resolved vs not resolved)Resolved STEMI · more with resolution | time between out-of-hospital and ED ECG acquisition 34 [25-52] vs 21 [14-27] minutes | P = 0.001 |
Ischemia on ED ECG in patients with non-STEMI out-of-hospital ECGs
- More defibrillations were associated with increased ischemia on ED ECG
Original publication
Associations with resolution of ST-segment elevation myocardial infarction criteria on out-of-hospital 12-lead electrocardiograms following resuscitation from cardiac arrest. Resuscitation. Published 6 March 2025. doi:10. 1016/ j. resuscitation. 2025. 110567
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