Congenital heart disease

Atherosclerotic Risk Factor Prevalence in Adults With Congenital Heart Disease: A Meta-Analysis

JACC AdvPublished Systematic review and meta-analysis

Authors' conclusion

Except for DM and smoking, the prevalence of traditional ASCVD risk factors is similar in ACHD compared to the general population.

Study context

Population
Adults with congenital heart disease (mean age 39 years; 52% males; 88% simple/moderate complexity)62 studies (30 controlled)
Participants
110,469 adults
Comparison
Adults with congenital heart disease (ACHD) vs general population
Outcome
Prevalence of traditional ASCVD risk factors (hypertension, dyslipidemia, DM, obesity, smoking, physical inactivity)
Methodological detailsLiterature search up to May 15, 2024
  • Literature search up to May 15, 2024

Pooled result

As reported in the abstract

Prevalence of ASCVD risk factors in ACHD
GroupLack of regular exerciseHypertensionObesityDyslipidemiaCurrent smokingDM
ACHD54% (45%-63%)33% (26%-40%)18% (14%-22%)17% (11%-25%)12% (9%-14%)7% (5%-9%)

ACHD

Lack of regular exercise54% (45%-63%)
Hypertension33% (26%-40%)
Obesity18% (14%-22%)
Dyslipidemia17% (11%-25%)
Current smoking12% (9%-14%)
DM7% (5%-9%)

Original publication

Atherosclerotic Risk Factor Prevalence in Adults With Congenital Heart Disease: A Meta-Analysis. JACC Adv. Published 19 October 2024. doi:10.1016/j.jacadv.2024.101359

Summarised from the published abstract; every number is checked against it

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