Arrhythmias & electrophysiologyCohort study

Atrial fibrillation and risk of sudden cardiac arrest in young adults

EuropacePublished

  • Retrospective cohort study
  • nationwide

Authors' conclusion

Atrial fibrillation was associated with a significantly higher risk of SCA developing in healthy young adults.

Study context

Population
Young adults aged 20–39 years undergoing health check-ups 2009–2012, South Korean nationwide healthcare database
Participants
6,345,162 adults
Exposure
Atrial fibrillation (AF) vs no AF
  • AFn = 5,875
Outcome
Sudden cardiac arrest (SCA)
Follow-up
Mean 9.4 years

Main finding

SCA

Adjusted hazard ratio

2.96

95% CI 1.99–4.41

P < 0.001

By group

AF vs No AF
adjusted HR 2.96 (95% CI 1.99–4.41); P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

Sudden cardiac arrest (SCA), incident vs prevalent AF

Both incident and prevalent AF associated with increased SCA risk, no significant difference between the two

Original publication

Atrial fibrillation and risk of sudden cardiac arrest in young adults. Europace. Published 19 July 2024. doi:10.1093/europace/euae196

Summarised from the published abstract; every number is checked against it