Arrhythmias & electrophysiology
Atrial Topology for a Unified Understanding of Typical and Atypical Flutter
Authors' conclusion
Combining topology with the index theorem offers a novel and cohesive framework for understanding and managing typical and atypical flutter.
Study context
- Population
- Cases of typical and atypical flutter (macroreentrant atrial tachycardia)106 left atrium, 25 right atrium
- Participants
- 131 cases
- Outcome
- Topological features of macroreentrant atrial tachycardia (modelling) and explanation of clinical activation, entrainment and ablation responses
Methodological detailscomputational spherical mesh model, clinical database
- Computational spherical mesh model
- Clinical database
Main finding
As reported in the abstract
- Reentry on closed surfaces consistently manifests as paired rotation
- An odd number of critical boundaries is mathematically impossible
- Unifying construct (with index theorem) explained number of loops, PPI-TCL values and ablation outcomes (termination, no change or TCL prolongation) in all 131 cases
Original publication
Atrial Topology for a Unified Understanding of Typical and Atypical Flutter. Circ Arrhythm Electrophysiol. Published 5 November 2024. doi:10. 1161/ circep. 124. 013102
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