Valvular & structural heart disease
Biphasic Right Ventricular Reverse Remodeling Following Tricuspid Valve Transcatheter Edge-to-Edge Repair
Authors' conclusion
RVRR following T-TEER occurs in 2 stages and involves early RV unloading (reduction in RVEDV3D) and later structural RVRR (reduction in RVESV3D) with an improvement in RVEF.
Study context
- Population
- Patients undergoing transcatheter tricuspid valve edge-to-edge repair (T-TEER) with 3D echocardiograms at baseline and discharge
- Participants
- 231 patients
- Outcome
- RV reverse remodeling on 3D echocardiography (RV end-diastolic and end-systolic volumes, RV EF, RV longitudinal strain)
- Follow-up
- 2-year follow-up
Methodological detailssequential 3D echocardiography
- Sequential 3D echocardiography
Main finding
As reported in the abstract
RV reverse remodeling after T-TEER
- RVEDV3D change from baseline to discharge
- −9.7%; P < 0.001
- RVESV3D change from baseline to 6-month follow-up
- −5.4%; P < 0.001
- RVEF3D at baseline
- 42.2% ± 8.9%
- RVEF3D at discharge
- 31.1% ± 9.4%
- RVEF3D at 2-year follow-up
- 41.6% ± 8.9%
Observational data: associations, not effects.
Original publication
Biphasic Right Ventricular Reverse Remodeling Following Tricuspid Valve Transcatheter Edge-to-Edge Repair. JACC Cardiovasc Interv. Published 9 December 2024. doi:10.
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