Heart failure & cardiomyopathies

BUN-to-ALB Ratio as an Effective Predictor of 30 Day Mortality in Acute Decompensated HF (ADHF) Patients in Eastern China

ESC Heart FailPublished Cox regression, restricted cubic spline and ROC curve analysis of admitted ADHF patients

Main finding · 30 day mortalityResult — go to the resultHazard ratio 3.25 95% CI 1.28–8.30

Authors' conclusion

This study found that BAR can serve as an effective predictor of short-term prognosis in ADHF patients based on clinical data from the Jiangxi population, with an optimal predictive threshold calculated at 0.33.

Study context

Population
ADHF patients admitted to Jiangxi Provincial People's Hospital from 2019 to 2022patients included in the analysis
Participants
1,421 patients
Comparison
High BAR vs low BAR
Outcome
30 day mortality
Follow-up
Median 30 day

Main finding

As reported in the abstract

Hazard ratio

3.25

95% CI 1.28–8.30

By group

high-BARvs low-BAR
HR 3.25 (95% CI 1.28–8.30)

Further findings

OutcomeHR (95% CI)
30 day mortality among those with concomitant cerebral infarction (subgroup)19.12 (2.67–136.67)

Nonlinear association between BAR and short-term mortality (restricted cubic spline)

P for nonlinearity
<0.001
Potential threshold effect when BAR was between 0.3 and 0.5

Predictive accuracy of BAR for short-term mortality (ROC)

AUC
0.84
Predictive efficiency
≈84%
Optimal threshold
0.33

Original publication

BUN-to-ALB Ratio as an Effective Predictor of 30 Day Mortality in ADHF Patients in Eastern China. ESC Heart Fail. Published 1 April 2025. doi:10.1002/ehf2.15289

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