Can incidental physical activity offset the deleterious associations of sedentary behaviour with major adverse cardiovascular events?
Authors' conclusion
Brief intermittent bursts of vigorous incidental physical activity may offset cardiovascular risks from high sedentary behaviour.
Study context
- Population
- Non-exercising adults, UK Biobank accelerometry sub-study (median age 62.9 years; 41.8% male)819 major adverse cardiovascular events (MACE) events
- Participants
- 22,368 adults
- Exposure
- Joint categories of incidental physical activity and sedentary behaviour
- Outcome
- MACE
- Follow-up
- 8.0-year median
Methodological detailsUK Biobank accelerometry sub-study, tertile-based joint associations
- UK Biobank accelerometry sub-study
- Tertile-based joint associations
Main finding
As reported in the abstract
MACE
Each group vs highest physical activity, lowest sedentary timeHazard ratio (95% CI)
High sedentary, low incidental VPA
1.34(0.98–1.84)
High sedentary, low incidental MVPA
1.89(1.42–2.52)
- VPA or vigorous intermittent lifestyle physical activity (VILPA) that may offset MACE risk of high sedentary behaviour
- 4.1 min/day
- Incidental MVPA largely attenuating associations with MACE
- 31-65 min
- Moderate to vigorous intermittent lifestyle physical activity (MV-ILPA) per day largely attenuating associations with MACE
- 26-52 min
Observational data: associations, not effects.
Original publication
Can incidental physical activity offset the deleterious associations of sedentary behaviour with major adverse cardiovascular events? Eur J Prev Cardiol. Published 26 September 2024. doi:10.
Summarised from the published abstract; every number is checked against it