Acute cardiac care & resuscitationCohort study

Cardiac Arrest During Long-Distance Running Races

JAMAPublished

  • Observational case series
  • registry-based
  • comparison with historical reference (2000-2009)

Authors' conclusion

Despite increased participation in US long distance running races, cardiac arrest incidence remains stable. There has been a marked decline in cardiac arrest mortality, and coronary artery disease was the most common etiology among cases with sufficient cause-related data.

Study context

Population
US marathon and half-marathon race finishers176 cardiac arrests
Participants
29,311,597 participants
Exposure
2010-2023 vs 2000-2009
  • 2010-2023n = 29,311,597
Outcome
Incidence proportions of sudden cardiac arrest and death

Main finding

As reported in the abstract

Incidence of cardiac arrest and cardiac death during races, 2010-2023 vs 2000-2009

Cardiac arrests among 29 311 597 race finishers

176

Cardiac arrest incidence unchanged vs 2000-2009

0.54 per 100 000 participants [95% CI, 0.41-0.70] vs 0.60 per 100 000 [95% CI, 0.52-0.70]

Significant decline in cardiac death incidence vs 2000-2009

0.20 per 100 000 [95% CI, 0.15-0.26] vs 0.39 per 100 000 [95% CI, 0.28-0.52]

Significant decline in case fatality rate vs 2000-2009

34% vs 71%

Observational data: associations, not effects.

Further findings

OutcomeValues
Cardiac arrest incidence by sexMen 1.12 per 100 000 (95% CI 0.95–1.32) · Women 0.19 per 100 000 (95% CI 0.13–0.27)
Cardiac arrest incidence by race distanceMarathon 1.04 per 100 000 (95% CI 0.82–1.32) · Half-marathon 0.47 per 100 000 (95% CI 0.38–0.57)
  • Cardiac arrest incidence by sex: 30 sex unknown

Etiology (definitive cause determined in 67/128 [52%])

CAD rather than hypertrophic cardiomyopathy the most common etiology

Factors associated with survival

Decreased cardiopulmonary resuscitation time and initial ventricular tachyarrhythmia rhythm associated with survival

Original publication

Cardiac Arrest During Long-Distance Running Races. JAMA. Published 20 May 2025. doi:10.1001/jama.2025.3026

Summarised from the published abstract; every number is checked against it