Acute cardiac care & resuscitation
Clinical Phenotyping of Cardiogenic Shock at a Glance: A Rapid, Costless, Streamlined Approach
Authors' conclusion
A simple clinical bedside evaluation of the CS phenotype based on hypotension, congestion and mottling allows for quick and costless stratification of 30-day mortality risk and can be used to guide the level of monitoring intensity and/or patient management.
Study context
- Population
- Patients with cardiogenic shock (CS)CS patients included in the analysis, from a registry of 772 CS patients
- Participants
- 475 patients
- Exposure
- Clinical phenotypic groups based on congestion, hypotension and skin mottling at admission
- Outcome
- All-cause mortality
- Follow-up
- 30 days
Methodological details49 centres
- 49 centres
Main finding
As reported in the abstract
Odds ratio (CI)P value
Hypotension and congestion
1.19(1.02–1.39)
P = 0.03Hypotension, congestion and mottling
1.26(1.08–1.48)
P < 0.01- Overall deaths at 30 days
- 113 patients (23.8%)
Observational data: associations, not effects.
Further findings
Baseline characteristics · admission
- Male
- 69.7%
- Median age
- 67.0 (59.0-78.0) years
- SCAI stage C
- 37.1%
- SCAI stage D
- 51.2%
- Congestion
- 424 patients (89.3%)
- Of those with congestion: both sides
- 50.7%
- Of those with congestion: left-sided
- 39.2%
- Of those with congestion: right-sided
- 10.1%
- Hypotension
- 343 (72.2%)
- Mottling
- 180 (37.9%)
Original publication
Clinical Phenotyping of Cardiogenic Shock at a Glance: A Rapid, Costless, Streamlined Approach. ESC Heart Fail. Published 19 May 2025. doi:10.
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