Cardiac complications in children with acute COVID-19 vs multisystem inflammatory syndrome in children (MIS-C)
Authors' conclusion
Cardiac involvement is much more common in children with MIS-C than in those with acute COVID-19.
Study context
- Population
- Children admitted with symptomatic acute COVID-19 or MIS-C, March 2020 to August 2021
- Participants
- 346 vs 304
- Exposure
- Acute COVID-19 vs MIS-C
- Acute COVID-19n = 346reference
- MIS-Cn = 304
- Outcome
- Cardiac involvement (≥1 of: elevated troponin, elevated brain natriuretic peptide, reduced LVEF or coronary dilation on echocardiogram, abnormal ECG)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Cardiac involvement
Observational data: associations, not effects.
Further findings
| Outcome | Acute COVID-19 | MIS-C |
|---|---|---|
| Most common cardiac abnormality | ||
| Abnormal ECG | 7.5% | — not stated in the abstract |
| Elevated troponin | — not stated in the abstract | 67.8% |
— not stated in the abstract
Factors associated with cardiac involvement
- Acute COVID-19: obesity significantly associated with cardiac involvement
- MIS-C: non-Hispanic Black race/ethnicity significantly associated with cardiac involvement
Original publication
Cardiac complications in children with acute COVID-19 vs multisystem inflammatory syndrome in children (MIS-C). Am Heart J. Published 20 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →