Cardiac Magnetic Resonance Imaging in COVID-19 Vaccine-Associated Myocarditis Compared With Classical Myocarditis
Authors' conclusion
Our study shows similar CMR imaging findings and short-term outcomes in PVM and CM, although PVM was associated with milder myocardial abnormalities and more frequent pericardial involvement.
Study context
- Population
- Patients with myocarditis undergoing cardiac magnetic resonance (CMR)
- Participants
- 31 vs 46
- Exposure
- COVID-19 mRNA postvaccination myocarditis vs classical myocarditis
- Postvaccination myocarditis (PVM)n = 31
- Classical myocarditis (CM)n = 46reference
- Outcome
- CMR imaging findings and short-term clinical outcomes (HF hospitalizations and mortality)
Main finding
As reported in the abstract
CMR findings
CMR findings
Pericardial effusion PVM 42% · CM 17% · P = 0.018
Pericardial LGE PVM 38% · CM 13% · P = 0.009
- PVM vs CM: P = 0.032 — T1 values
Observational data: associations, not effects.
Further findings
Events
| Outcome | PVM | CM |
|---|---|---|
| Death or HF hospitalization · median 300 days for PVM, 319 days for CM | 0 | 0 |
Original publication
Cardiac Magnetic Resonance Imaging in COVID-19 Vaccine-Associated Myocarditis Compared With Classical Myocarditis. JACC Adv. Published 24 November 2023. doi:10.
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