Cardiac Magnetic Resonance to Predict Cardiac Mass Malignancy: The Cardiac Magnetic Resonance (CMR) Mass Score
An erratum to this article was published (Circ Cardiovasc Imaging, Sep 2024 ↗)
Authors' conclusion
A CMR-derived model, including mass morphology and tissue characterization, showed excellent accuracy, superior to echocardiography, in predicting cardiac masses malignancy, with prognostic implications.
Study context
- Population
- Patients with suspected cardiac mass undergoing echocardiogram and CMR within 1 month; histology or thrombus resolution as reference
- Participants
- 167 patients
- Comparison
- CMR mass score vs Diagnostic echocardiographic mass score
- Outcome
- Accuracy in predicting cardiac mass malignancy (histology as gold standard)
Methodological detailsobservational cohort, consecutive patients
- Observational cohort
- Consecutive patients
Performance
As reported in the abstract
Malignancy prediction
| Test or model | AUC |
|---|---|
| CMR mass score | 0.976 (95% CI 0.96-0.99) |
| Diagnostic echocardiographic mass score | 0.932 |
AUC
CMR mass score0.976 (95% CI 0.96-0.99)
Diagnostic echocardiographic mass score0.932
- CMR mass score vs Diagnostic echocardiographic mass score: P = 0.040 — CMR significantly higher
Further findings
| Outcome | HR | P value |
|---|---|---|
| All-cause death, CMR mass score ≥5 · follow-upCMR mass score ≥5 vs CMR mass score <5 | 5.70 | P < 0.001 |
Agreement between echocardiographic and CMR mass scores
- Good agreement (κ)
- 0.66
Original publication
Cardiac Magnetic Resonance to Predict Cardiac Mass Malignancy: The CMR Mass Score. Circ Cardiovasc Imaging. Published 19 March 2024. doi:10.
Summarised from the published abstract; every number is checked against it