Aortic & peripheral vascular disease
Cardiac Tamponade Complicating Type A Acute Aortic Dissection: Insights From 25 Years of Registry Research
Authors' conclusion
TMP is an important prognosticator of in-hospital mortality. It is associated with increased mortality of TAAAD and prompt surgery is required. Those who survive the hospital course, go on to share the same postdischarge course as those who did not have TMP.
Study context
- Population
- Patients with type A acute aortic dissection (TAAAD), with and without preoperative cardiac tamponadepatients with TAAAD, 865 (14.4%) developed tamponade (TMP)
- Participants
- 6,014 patients
- Exposure
- TAAAD patients with and without preoperative TMP were compared
- TMPn = 865
- Outcome
- In-hospital mortality
Methodological details63 aortic centers, 1996 to 2022, multivariable modeling, survival curves
- 63 aortic centers
- 1996 to 2022
- Multivariable modeling
- Survival curves
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
Age · older with TMP
P < 0.0001
Male sex · less often male with TMP
P = 0.005
Prior cardiac surgery · less common with TMP
P < 0.0001
Syncope on presentation · more frequent with TMP
P < 0.0001
Coma or altered consciousness on presentation · more frequent with TMP
P < 0.0001
Surgical management · similar
P = 0.911
- 4-year survival · 4 years · similar
- log-rank P = 0.767
Time to presentation or diagnosis
- No differences were seen in time to presentation or diagnosis
Follow-up
- Overall median follow-up
- 35.8 months (Q1-Q3: 11.6-59.4 months)
Original publication
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