Arrhythmias & electrophysiology

Cardiac tamponades related to interventional electrophysiology procedures are associated with higher risk of short-term hospitalization for pericarditis but favourable long-term outcome

EuropacePublished Matched cohort study

Main findingResult — go to the resultHazard ratio 1.22 95% CI 0.79–1.88

Authors' conclusion

In this nationwide cohort of patients undergoing invasive EPs, iatrogenic cardiac tamponade was associated with an increased risk of hospitalization for pericarditis during the first months after the index procedure. In the long-term, however, cardiac tamponade revealed no significant association with mortality or other serious cardiovascular events.

Study context

Population
Patients undergoing invasive electrophysiology procedures, Swedish Catheter Ablation Registry, 2005–201958,770 electrophysiology procedures (EPs) in 44,497 patients
Participants
200 vs 400
Exposure
Iatrogenic cardiac tamponade vs no tamponade after invasive EPs
  • Tamponaden = 200
  • Controln = 400reference
Outcome
Composite of:
  • All-cause death
  • Acute MI
  • Transitory ischaemic attack (TIA)/stroke
  • HF hospitalization
Follow-up
5 years
Methodological detailsnationwide, Swedish Catheter Ablation Registry
  • Nationwide
  • Swedish Catheter Ablation Registry

Main finding

As reported in the abstract

Hazard ratio

1.22

95% CI 0.79–1.88

Tamponadevs Control
HR 1.22 (95% CI 0.79–1.88)

Observational data: associations, not effects.

Further findings

Single components of the primary endpoint and CV death

No statistically significant association with cardiac tamponade

Safety

OutcomeHR (95% CI)
Hospitalization for pericarditis20.67 (6.32–67.60)

Original publication

Cardiac tamponades related to interventional electrophysiology procedures are associated with higher risk of short-term hospitalization for pericarditis but favourable long-term outcome. Europace. Published 12 June 2023. doi:10.1093/europace/euad140

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