Arrhythmias & electrophysiology
Trends in safety of catheter-based electrophysiology procedures in the last 2 decades: A meta-analysis
Authors' conclusion
Despite an increase in cardiac electrophysiology procedures, procedural safety has improved over time.
Study context
- Population
- Patients undergoing AF ablation, ventricular tachyarrhythmia ablation, leadless cardiac pacemaker implantation or percutaneous LAAO
- Participants
- 43,914 patients174 studies
- Comparison
- Complication rates, publication years 2000-2018 vs 2019-2023
- Outcome
- Serious procedure-related complications
Methodological detailsprospective trials or registries, random effects models, AF ablation: 126 studies, n = 24,057; VT ablation: 25 studies, n = 1781; leadless pacemaker: 21 studies, n = 8896; LAAO: 18 studies, n = 9180
- Prospective trials or registries
- Random effects models
- AF ablation: 126 studies, n = 24,057; VT ablation: 25 studies, n = 1781; leadless pacemaker: 21 studies, n = 8896; LAAO: 18 studies, n = 9180
Pooled result
As reported in the abstract
P < 0.001
Further pooled results
Procedure-related death
P = 0.003
Safety
Serious procedure-related complications (pooled incidence) · significantly decreased over time
P < 0.001
Procedure-related stroke, pericardial effusion requiring intervention, procedure-related death (pooled incidence)
- Procedure-related stroke 0.46% vs 0.28%, significantly decreased over time
- P = 0.002
- Pericardial effusion requiring intervention 1.02% vs 0.83%, significantly decreased over time
- P = 0.037
- Procedure-related death 0.15% vs 0.06%, significantly decreased over time
- P = 0.003
Vascular complications (pooled incidence)
- No significant difference in incidence over time (1.86% vs 1.88%)
- P = 0.888
Original publication
Trends in safety of catheter-based electrophysiology procedures in the last 2 decades: A meta-analysis. Heart Rhythm. Published 16 May 2024. doi:10.
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