Acute cardiac care & resuscitation
Cardiogenic shock as a complication of acute myocardial infarction: a nationwide cohort study
Authors' conclusion
The in-hospital mortality rates for AMI-related CS remain high, especially in patients ≥75 years. However, long-term mortality in CS patients surviving to hospital discharge was only moderately higher compared with AMI patients without CS.
Study context
- Population
- All patients <85 years with acute myocardial infarction (AMI) registered in the Norwegian Myocardial Infarction Registry 2013–2022AMI patients (40% women) · cardiogenic shock (CS), <75 years 1,645 · CS, 75-84 years 969
- Participants
- 86,730 patients
- Exposure
- Patients with AMI complicated by CS compared with those without CS
- Outcome
- Incidence of CS
Methodological detailsnationwide
- Nationwide
Main finding
As reported in the abstract
<75 years
1645
2.7%
75-84 years
969
3.9%
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted HR (95% CI) | |
|---|---|---|
| Long-term mortality among patients who survived to hospital dischargeAMI-CS vs without CS · <75 years · multivariable Cox regression | 1.91 (1.67–2.18) | |
| Long-term mortality among patients who survived to hospital dischargeAMI-CS vs without CS · 75-84 years · multivariable Cox regression | 1.65 (1.41–1.93) | |
| 0.512Adjusted hazard ratio (log scale) |
In-hospital mortality in AMI-CS patients
- AMI-CS <75 years
- 47.5%
- AMI-CS 75-84 years
- 71.4%
Estimated one year cumulative mortality in AMI-CS patients
- AMI-CS <75 years
- 54.7% (95% CI: 52.3-57.1%)
- AMI-CS 75-84 years
- 79.8% (95% CI: 77.2-82.3)
Baseline characteristics
- Regardless of age, patients with AMI-CS were more likely to have previous heart failure, diabetes, renal failure, and ST-elevation AMI compared with patients without CS
Original publication
Cardiogenic shock as a complication of acute myocardial infarction: a nationwide cohort study. Eur Heart J Acute Cardiovasc Care. Published 19 September 2025. doi:10.
Summarised from the published abstract; every number is checked against it