Cardiovascular health effects of vaping e-cigarettes: a systematic review and meta-analysis
Authors' conclusion
This review highlighted several important cardiovascular impacts of e-cigarette use compared with non-use and cigarette smoking. However, the evidence is still limited and requires future research.
Study context
- Population
- Peer-reviewed human, animal, cell/in vitro original studies of e-cigarette exposure published between July 2021 and December 2023studies in the main analysis, 12 in the meta-analysis, 32 in the sociodemographic subgroup analysis · main analysis 63 · meta-analysis 12 · sociodemographic factor-based subgroup analysis 32
- Participants
- 63 studies
- Comparison
- E-cigarette use compared with non-use and cigarette smoking
- Outcome
- Heart rate and blood pressure after acute exposure
- Follow-up
- Acute exposure
Pooled result
As reported in the abstract
MD
11.329
P < 0.01
HR, increased with e-cigarette
MD
12.856
P < 0.01
systolic blood pressure (BP), increased with e-cigarette
MD
7.676
P < 0.01
diastolic BP, increased with e-cigarette
Further pooled results
| Outcome | MD | P value |
|---|---|---|
| Heart rate and blood pressure after acute exposure, e-cigarettes vs cigarettesHR lower with e-cigarettes | −5.415 | P < 0.01 |
| Resting HR and BP, non-smoker current vapersNon-smoker current vapers vs non-vaper current smokers · resting HR lower in vapers | −2.608 | P < 0.01 |
| Resting HR and BP, non-smoker current vapersNon-smoker current vapers vs non-vaper current smokers · diastolic BP lower in vapers | −3.226 | P < 0.01 |
Heart rate and blood pressure after acute exposure, e-cigarettes vs cigarettes
- No significant difference in systolic or diastolic BP
Resting HR and BP, non-smoker current vapers
- No significant differences in resting HR and BP compared with non-users
Endothelial function, blood flow and BP · short-to-medium term
- Some association between e-cigarette and endothelial dysfunction; transition from cigarettes to e-cigarettes may improve blood flow and BP, particularly among females and younger individuals
Cardiovascular diseases and cardiac dysfunction or remodelling
- Lack of evidence supporting any association with e-cigarette use
Risk of bias
- Over half of the human studies had low risk of bias
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →