Cardiovascular Risk Prediction Scores in Type 1 Diabetes: A Systematic Review and Meta-Analysis
Authors' conclusion
Among individuals with T1DM, CVD risk models had a moderate to excellent discrimination, with a better discrimination and accuracy for T1DM-specific scores.
Study context
- Population
- Persons with T1DM (mean age 34 years, mainly White, 55% male)
- Participants
- 73,664 persons11 studies
- Comparison
- T1DM-specific cardiovascular disease (CVD) risk scores vs general population or type 2 diabetes risk scores
- T1DM-specificn = 7
- Outcome
- Discrimination (C-statistic) and calibration of CVD risk scores
Methodological detailsrandom-effects models
- Random-effects models
Pooled result
As reported in the abstract
Discrimination (C-statistic)
T1DM-specific
0.81
pooled C-statistic
General population or type 2 diabetes
0.75
pooled C-statistic
- Most risk scores had moderate to excellent discrimination (C-statistic range)
- 0.73-0.85
Original publication
Cardiovascular Risk Prediction Scores in Type 1 Diabetes: A Systematic Review and Meta-Analysis. JACC Adv. Published 17 December 2024. doi:10.
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