Cardiovascular risk profiles in patients with inflammatory bowel disease differ from matched controls from the general population
Corrected 23 Oct 2026: The mean 10-year SCORE2 risk is shown as its own result; the odds ratios and differences for ASCVD events and risk factors stand apart from it.
Authors' conclusion
The increased CVD risk in IBD is discrepant with the 10-year CVD risk estimate.
Study context
- Population
- Patients with inflammatory bowel disease aged ≥45 years and matched controls from the general population
- Participants
- 235 vs 829
- Exposure
- Inflammatory bowel disease (IBD) patients vs age/sex-matched controls from the general population
- IBDn = 235
- Controlsn = 829reference
- Outcome
- Cardiovascular disease (CVD) risk factors and 10-year CVD risk (Systematic COronary Risk Evaluation (SCORE2))
Methodological detailsage/sex-matched controls
- Age/sex-matched controls
Main finding
As reported in the abstract
IBD vs ControlsOdds ratio (95% CI)
ASCVD events
2.01(1.23–3.27)
Overweight
0.48(0.35–0.66)
Hypercholesterolaemia
0.45(0.31–0.65)
Hypertension
1.67(1.19–2.32)
- Waist circumference
- difference +4 cm; P = 0.006
- Triglyceride levels
- difference +0.6 mmol/L; P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| ASCVD events by typeHF | 2.02 (1.02–4.01) | |
| ASCVD events by typeCHD | 2.01 (1.7–3.13) | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | IBD | Controls |
|---|---|---|
| Mean 10-year CVD risk (SCORE2) | mean 4.0% (SD 2.6) · n = 135 | mean 6.0% (SD 1.6) · n = 506 |
Original publication
Cardiovascular risk profiles in patients with inflammatory bowel disease differ from matched controls from the general population. Eur J Prev Cardiol. Published 19 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →