Arrhythmias & electrophysiology
Catheter ablation of atrial fibrillation and atrial tachycardia in patients with pulmonary hypertension: a randomized study
Primary resultResult — go to the resultHazard ratio 0.97 95% CI 0.49–2.0Authors' conclusion
Extensive ablation, compared with a limited approach, was not beneficial in terms of arrhythmia recurrence in patients with AF/AT and PH.
Study context
- Population
- Patients with combined post- and pre-capillary or isolated pre-capillary pulmonary hypertension and supraventricular arrhythmia (atrial fibrillation (AF)/AT) indicated for catheter ablation
- Participants
- 77 patients
- Comparison
- Extended ablation vs limited ablation
- Primary endpoint
- Arrhythmia recurrence >30 s without antiarrhythmic drugs
- Follow-up
- After the 3-month blanking period; median 13 (IQR 12; 19) months
Methodological detailsmulticentre (3 centres), 1:1 randomisation, parallel-group
- Multicentre (3 centres)
- 1:1 randomisation
- Parallel-group
Primary result
As reported in the abstract
Hazard ratio
0.97
95% CI 0.49–2.0
Events by treatment group
Extended ablation vs Limited ablation
HR 0.97 (95% CI 0.49–2.0)
Safety
Procedural complications and clinical follow-up events including all-cause death
- No excess in the Extended ablation group
Original publication
Catheter ablation of atrial fibrillation and atrial tachycardia in patients with pulmonary hypertension: a randomized study. Europace. Published 13 May 2023. doi:10. 1093/ europace/ euad131
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