Arrhythmias & electrophysiology

Causes of death in patients with atrial fibrillation anticoagulated with rivaroxaban: a pooled analysis of XANTUS

EuropacePublished Pooled analysis of the XANTUS programme studies

Authors' conclusion

The overall risk of death due to stroke or bleeding was low in XANTUS. Anticoagulated patients with AF remain at risk of death due to heart failure and sudden death.

Study context

Population
Patients with atrial fibrillation (AF) anticoagulated with rivaroxaban (XANTUS programme)
Participants
11,040 patients
Outcome
Causes of death and factors associated with all-cause and CV death
Follow-up
Within a year after rivaroxaban initiation
Methodological detailscentral adjudication of causes of death
  • Central adjudication of causes of death

Pooled result

As reported in the abstract

Death and causes of death
  • Independent factors associated with all-cause or CV death: age, AF type, BMI, LVEF, hospitalization at baseline, rivaroxaban dose, anaemia
  • Cause-of-death percentages are of the deaths (n = 187)

Further pooled results

Independent factors associated with all-cause or CV death

Age, AF type, BMI, LVEF, hospitalization at baseline, rivaroxaban dose, anaemia

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Causes of death in patients with atrial fibrillation anticoagulated with rivaroxaban: a pooled analysis of XANTUS. Europace. Published 29 June 2024. doi:10.1093/europace/euae183

Composed by AI from the published abstract and checked against it. How Briefs are made →

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